4-Amino-5-Chloro-2,3-Dihydrobenzo[B]Furan-7-Carboxylic Acid
4-Amino-5-chloro-2,3-dihydrobenzofuran-7-carboxylic acid
CAS: 123654-26-2
Molecular Formula: C9H8ClNO3
4-Amino-5-Chloro-2,3-Dihydrobenzo[B]Furan-7-Carboxylic Acid - Names and Identifiers
4-Amino-5-Chloro-2,3-Dihydrobenzo[B]Furan-7-Carboxylic Acid - Physico-chemical Properties
| Molecular Formula | C9H8ClNO3 |
| Molar Mass | 213.62 |
| Density | 1.566 |
| Melting Point | 242 °C(dec.) |
| Boling Point | 406.5±45.0 °C(Predicted) |
| Solubility | DMSO (Slightly), Methanol (Slightly, Heated) |
| Appearance | Solid |
| Color | Light Brown |
| pKa | 4.45±0.20(Predicted) |
| Storage Condition | 2-8°C(protect from light) |
4-Amino-5-Chloro-2,3-Dihydrobenzo[B]Furan-7-Carboxylic Acid - Reference Information
| Application | 4-amino-5-chloro-2, 3-dihydrobenzofuran-7-carboxylic acid is a carboxylic acid derivative, which can be used as a pharmaceutical intermediate. |
| preparation | . The method is to first add 4-(acetylamino) -2-hydroxy-3-(2-hydroxyethyl) benzoate methyl ester to an organic solvent, add triphenylphosphine and diethyl azodicarboxylate to close the ring to obtain 4-acetylamino -2, 3-dihydrobenzofuran-7-methyl acetate crude product, the crude product 4-acetamido-5-chloro-7-benzofuran-formate was directly chlorinated with N-chlorinated succinimide to obtain the crude product 4-acetamido-5-chloro-2-dihydrobenzofuran-7-carboxylic acid by hydrolysis and purification to obtain the pure product 4-amino-5-chloro-2, 3-dihydrobenzofuran-7-carboxylic acid. |
Last Update：2024-04-09 20:13:35
![4-Amino-5-Chloro-2,3-Dihydrobenzo[B]Furan-7-Carboxylic Acid](http://res.chembk.com/assets/str/2d/1/12/123654-26-2.png)
Supplier List
Spot supply
Product Name: Prucalopride Impurity 12 Visit Supplier Webpage Request for quotationCAS: 123654-26-2
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
Product Name: 4-Amino-5-chloro-2,3-dihydro-7-benzofurancarboxylic Acid Visit Supplier Webpage Request for quotation
CAS: 123654-26-2
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 123654-26-2
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
Spot supply
Product Name: Prucalopride Impurity 12 Visit Supplier Webpage Request for quotationCAS: 123654-26-2
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
Product Name: 4-Amino-5-chloro-2,3-dihydro-7-benzofurancarboxylic Acid Visit Supplier Webpage Request for quotation
CAS: 123654-26-2
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 123654-26-2
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
View History
4-Amino-5-Chloro-2,3-Dihydrobenzo[B]Furan-7-Carboxylic Acid
m-Chlorocarbanilic acid 4-(1-pyrrolidinyl)-2-butynyl ester
N-aminocarbonylethanediamide
m-Chlorocarbanilic acid 4-(1-pyrrolidinyl)-2-butynyl ester
N-aminocarbonylethanediamide